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BCRFA Awards Funds for Two Collaborative Breast Cancer Research Projects in Alabama

 Breast Cancer Research Foundation of Alabama (BCRFA) Awards Funds For Two Collaborative Breast Cancer Research Projects in Alabama

Oct. 12, 2018

The Breast Cancer Research Foundation of Alabama (BCRFA) has presented two awards for two-year collaborative breast cancer research projects within Alabama. One award went to Dr. David Schneider of UAB and Dr. Corinne E. Augelli-Szafran of Southern Research, and the second award will fund Dr. Gabrielle Roque of the UAB Comprehensive Cancer Center, Dr. Casey Daniel of USA Mitchell Cancer Institute, Dr. Alan Balch of the Patient Advocate Foundation, and Dr. Eric Ford of the UAB Department of Public Health. The selected projects will each receive $50,000 annually for two consecutive years, totaling $100,000 each over the two-year period.

 Schneider and Augelli-Szafran’s project, “Developing compounds to inhibit ribosome synthesis in triple negative breast cancer cells: A pathway toward novel chemotherapeutics,” will focus on advancing a new method for therapeutic control of breast cancer, creating derivatives of compounds with increased potency and solubility, and defining how these eliminate breast cancer growth.

 Roque, Daniel, Balch and Ford’s project, “Quantifying breast cancer patient preferences and their association with financial toxicity during treatment decision-making,” will create opportunities for patients to participate in decision-making, aid clinicians in understanding patient perspective during treatment decision-making, and ultimately achieve patient-centered, higher value healthcare for women living with breast cancer.

 The BCRFA will also continue a second year of support for the two funding awards made to last year’s winning proposals. Dr. Piazza and Dr. Grubbs’ project, “A Novel Wnt/β-Catenin Inhibitor for Breast Cancer,” is developing a promising experimental drug, MCI-030, for breast cancer prevention and treatment and further study its unique mechanism of action involving the suppression of Wnt/β-Catenin signaling and Drs. Berry, Deshane, Frost and Suto’s project, “A Humanized 3D Immunocompetant Model of Breast Cancer for Precision Medicine and Immune Therapy Development” is developing a 3D humanized immunocompetent breast cancer model that will enhance cancer drug development and advance personalized cancer therapy.

 The Breast Cancer Research Foundation of Alabama is a nonprofit organization raising funding and awareness for breast cancer research in Alabama.

 “Since the organization began in 1996, the BCRFA has invested over $7.7 million in breast cancer research initiatives in Alabama. We are excited to award these two grants supporting collaborative breast cancer research,” stated Beth Bradner Davis, BCRFA executive director. 

 With these collaboration awards, the Breast Cancer Research Foundation of Alabama hopes to: encourage collaboration among top researchers in Alabama in the field of breast cancer research; help support basic research which can be emerge into translational research; offer financial support to promising breast cancer research in Alabama providing seed money to enable a project to secure additional funding from national providers; and offer hope to those affected by breast cancer and ultimately save lives through breast cancer research.

 About the BCRFA
The Breast Cancer Research Foundation of Alabama supports a comprehensive approach to battling breast cancer through support of collaborative and innovative research to help diagnose, treat, prevent and eradicate the disease. Since its inception in 1996, the BCRFA has raised over $7.7 million to fund research at the UAB Comprehensive Cancer Center and with their collaborative partners. All funds raised stay here in the state of Alabama, but the research will have a global, life-saving impact.

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